Human genetic susceptibility toCandidainfections
نویسندگان
چکیده
منابع مشابه
Human genetic susceptibility to tuberculosis.
INTRODUCTION Recent advances in the understanding of human susceptibility to tuberculosis have resulted from the application of molecular techniques to answer mechanistic questions on genetic regulation of host defense. METHODS This review is based upon a MEDLINE search of articles relevant to human genetic susceptibility to mycobacteria. RESULTS The impact of natural selection in shaping s...
متن کاملHuman Genetic Susceptibility to Invasive Aspergillosis
Aspergillosis includes a wide spectrum of diseases caused by fungi of the genus Aspergillus with clinical manifestations that range from colonization (e.g., aspergilloma), to allergic bronchopulmonary aspergillosis, to disseminated forms of infection. Invasive aspergillosis (IA) has been estimated to occur in 10% of acute myeloid leukemia patients during post-induction aplasia or consolidation ...
متن کاملAnthrax Susceptibility: Human Genetic Polymorphisms Modulating ANTXR2 Expression
Anthrax toxin causes anthrax pathogenesis and expression levels of ANTXR2 (anthrax toxin receptor 2) are strongly correlated with anthrax toxin susceptibility. Previous studies found that ANTXR2 transcript abundance varies considerably in individuals of different ethnic/geographical groups, but no eQTLs (expression quantitative trait loci) have been identified. By using 3C (chromatin conformati...
متن کاملGenetic Susceptibility to Transient and Permanent Neonatal Diabetes Mellitus
Neonatal diabetes mellitus (NDM) is a rare kind of diabetes characterized by hyperglycemia and low levels of insulin. Clinically, it is categorized into two main types: transient NDM (TNDM) and permanent NDM (PNDM). These types are diagnosed based on duration of insulin dependence early in the disease. In TNDM, diabetes begins in the first few weeks of life with remission in a few months. Howev...
متن کاملCD38 gene polymorphisms and genetic susceptibility to chronic lymphocytic leukemia
Introduction: CLL is one of the most common leukemias, which is categorized by the accumulation of mature CD5+ B-lymphocytes in the peripheral blood, bone marrow, and secondary lymphoid organs. In this study, the status of rs6449182 polymorphism of the CD38 gene and its association with clinical and laboratory parameters of CLL patients was evaluated. Methods: Genomic DNA extraction was perfor...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2012
ISSN: 1369-3786,1460-2709
DOI: 10.3109/13693786.2012.690902